Today's Date: May 16, 2012

Products and Pipeline

Discovery Phase:
Scientific research conducted with the aim of developing a drug for a specific disease or medical condition.
Preclinical Phase:
Animal studies and laboratory tests to evaluate safety and efficacy, demonstrate activity of a product candidate and identify its chemical and physical properties.
Phase 1:
Clinical studies to test safety profile of drug in humans.
Phase 2:
Clinical studies conducted with groups of patients to determine preliminary efficacy, dosage and expanded evidence of safety.
Phase 3:
Large scale clinical studies conducted in patients to provide sufficient data for statistical proof of efficacy and safety.
Filed Phase:
Filed
Approved Phase:
Approved
Marketed Phase:
Marketed
Discovery Preclinical Phase 1 Phase 2 Phase 3 Filed Approved Marketed
ALZHEIMER'S DISEASE
ELND005
Beta Secretase Research
BIPOLAR DISORDER
ELND005
PARKINSON'S DISEASE
Parkinson's Research
MULTIPLE SCLEROSIS (WITH BIOGEN IDEC)
TYSABRI® (natalizumab) Relapsing forms of Multiple Sclerosis
TYSABRI® (natalizumab) Secondary Progressive Multiple Sclerosis
TYSABRI® Subcutaneous
CROHN'S DISEASE (WITH BIOGEN IDEC)
TYSABRI® (natalizumab) (U.S.)
NEOTOPE (NEO-EPITOPE TARGETS INCLUDING AD, AL, DIABETES)
Neotope Research
ONCLAVE (ONCOLOGY RELATED TARGETS)
Onclave Research

TYSABRI is a registered trademark of Elan Pharmaceuticals, Inc. in the United States and of Elan Pharma International Ltd. in various countries outside the United States.

®2009 Elan Pharmaceuticals, Inc. ELN 022 0104